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Symbol
Name
ID
Tlr4
toll-like receptor 4
MGI:96824
Phenotype annotations related to renal/urinary system
Darker colors indicate more annotations
Human Phenotypes
Hematuria
Decreased level of D-mannose in urine
Proteinuria
Renal amyloidosis
Nephrocalcinosis
Nephropathy
Nephrotic syndrome
Renal insufficiency
Stage 5 chronic kidney disease
Disease(s) Associated with TLR4
Behcet's disease
familial mediterranean fever
temporal arteritis

Mouse Phenotypes
renal tubular necrosis
decreased susceptibility to kidney reperfusion injury
abnormal renal tubule epithelium morphology
abnormal nephron morphology
abnormal renal tubule morphology
abnormal proximal convoluted tubule brush border morphology
dilated renal tubule
renal cast
Availability Mouse Genotype
Tlr4tm1Aki/Tlr4tm1Aki

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory